Pr. Daniel HUBER Group

Neural circuits and behavior

Whether it is for tying one’s shoe laces or exploring the iPhone, we need to continuously practice new movements and acquire novel motor skills. Motor cortex is one of the key brain areas participating in
coordinating and learning of such voluntary movements. Despite decades of research this brain area remains poorly understood. The general aim of our lab is to use a series of innovative optical imaging methods, such as in vivo two-photon microscopy, to record neuronal activity in the motor cortex with single cell resolution and thereby gain a better understanding of the exact neuronal network dynamics underlying motor control and skill learning. We will use mice as model system since they are great manipulators and give access to a wide variety of important molecular tools and to well established models motor diseases. These experiments in rodents will ultimately help us to understand some of the basic neuronal mechanisms that govern our own actions, enabling us to solve new challenges.